Genicular Knee Ablation For Osteoarthritis of the Knee Genicular knee ablation is a minimally invasive procedure that is used to treat osteoarthritis of the knee. It involves the use of three thin needles to block genicular nerves at the confluence of the femur and tibia. The doctor will first numb the area with a local anesthetic and use a fluoroscope to guide the needle. The physician will then insert a cannula near the genicular nerve. This nerve is blocked by the numbing injection, and pain