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2:43
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DRdoubleB
Invasion, Metastasis and Angiogenesis
An animation explaining the steps in invasion, metastasis, and angiogenesis. 1. Loss of adhesion molecules such as e-cadherin 2. Upregulation of fibronectin/laminin receptors to bind basement membrane 3. Production of collagenases to break down Type IV collagen of basement membrane 4. Autocrine signaling promoting cytokinesis 5. Intravasation ...
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