Video: Preparation of Amines: Reductive Amination of Aldehydes and Ketones
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Video: Preparation of Amines: Reductive Amination of Aldehydes and Ketones
Carbonyl compounds and primary amines undergo reductive amination first to produce imines, followed by secondary amines in the same reaction mixture, using selective reducing agents like sodium cyanoborohydride or sodium triacetoxyborohydride.
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Reductive Amination Mechanism
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