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Fischer Indole Synthesis
7:44
YouTubeProfessor Dave Explains
Fischer Indole Synthesis
We've talked about a few heterocycles, but one important aromatic one we didn't mention is the indole. This is a component of a variety of biomolecules. So how can we make them? Nobel prize winner Emil Fischer developed the Fischer indole synthesis in 1882 to do precisely this, using aryl hydrazines and ketones. What's the mechanism? Is that a ...
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