This important study builds on previous work from the same authors to present a conceptually distinct workflow for cryo-EM reconstruction that uses 2D template matching to enable high-resolution ...

PEGASUS generates permeable macrocyclic peptides, offering new promise for a modality that can combine the properties of a biologic in a pill ...

Trained on 9.7 trillion tokens of evolutionary data, EDEN designs therapeutics from large gene insertion to antimicrobial peptides.

Cancer evolves through layers of change: mutations in DNA, shifts in gene regulation, altered cell behaviour, and dynamic ...

Background IBD is characterised by recurrent flares, but evidence on whether modifiable dietary factors influence flare risk ...

Amanpal Dhupar, Head of Retail at Tredence is an experienced retail analytics and AI leader with over a decade of expertise in designing and developing data-driven solutions that deliver actionable ...

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely silence a brain receptor that pharmaceutical companies are racing to target ...

Artificial intelligence (AI) and “protein language” models can speed the design of monoclonal antibodies that prevent or reduce the severity of potentially life-threatening viral infections, according ...

A rare genetic variant found in families affected by schizophrenia completely abolishes the function of TAAR1, an emerging drug target for psychiatric disorders. The C182F mutation causes a 40% ...

Cancer therapy and synthetic biology are converging around a shared problem that has long frustrated oncologists and ...