Immunotherapy is increasingly becoming standard therapy in cancer, with technology, such as checkpoint inhibitors and cell therapy, raising the efficacy bar in many forms of the disease. But the ...

Figure 1: Effect of deficient local C3 synthesis on transplant survival and function. To assess the influence of circulating C3, we transplanted a group of C3 −/− recipients (n = 6) with normal ...

Among people with sickle cell disease—an inherited blood disorder—acute chest syndrome (ACS) is the leading cause of death. The condition is the result of red blood cells becoming stiff, sticky, and ...