Figure 1: Ribavirin resistance in patients and cell lines. To determine the clinical relevance of these observations, we examined UGT1A protein levels during response and relapse using confocal ...

Oncotarget published "Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer" which reported that Glucuronidation controls ...

Phase I evaluation of troxacitabine administered by continuous infusion in patients with refractory solid tumors No significant financial relationships to disclose. This is an ASCO Meeting Abstract ...

Environmental Health Perspectives, Vol. 105, Supplement 4 (Jun., 1997), pp. 739-747 (9 pages) Glucuronidation and sulfation are phase 2 metabolic reactions catalyzed by large families of different ...

Fluorouracil and leucovorin with or without interferon alfa-2b in advanced colorectal cancer: analysis of a prospective randomized phase III trial. Hellenic Cooperative Oncology Group. Twenty-six men ...

Kanazawa, Japan - One of the main functions of the liver is to detoxify compounds including drugs and toxicants to reduce toxic actions and to eliminate from the human body, requiring a molecular ...