Pyruvate kinase PEP + ADP Pyruvate + ATP Glycolysis Catalyzes last step of glycolysis; irreversible reaction. Enzyme activated by feed forward action fructose 1,6-bisphosphate; synthesis stimulated by ...
Figure 1: Structure of ATP-bound tetrameric PFKP is in the active conformation. Figure 3: Interactions at the tetramer interface of PFKP regulate enzyme activity. In addition to cancer, aberrant ...
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