A robust primary immune response has been correlated with the precursor number of antigen-specific T cells, as identified using peptide MHCII tetramers. However, these tetramers identify only the ...

An international team led by two Université de Montréal researchers has unveiled how a molecule capable of opening the "shell ...

A 45-year-old active substance user began getting medical care in your clinic in 1997. He had started taking antiretrovirals (nelfinavir + Combivir) at another facility. Initial labs showed an ...

Rochester, MN - Rheumatoid arthritis (RA)-associated lung disease is different from idiopathic pulmonary fibrosis, researchers say, pointing to an increased number of CD4+ T cells. A new study in the ...

For adults infected with HIV in Thailand a monitoring strategy based on CD4 count (a type of white blood cell) is non-inferior to the recommended monitoring strategy measuring the amount of HIV virus ...

Paper in Nature Structural & Molecular Biology suggests that 21c-type antibody-eliciting vaccines will need to overcome elimination mechanisms. California Institute of Technology researchers report on ...

This is a preview. Log in through your library . Abstract Intermittent interleukin-2 (IL-2) therapy has been shown to increase the number of CD4+ T cells, preferentially cells with a naive phenotype, ...

This is a preview. Log in through your library . Abstract Helper T-cell activation generally requires the coreceptor CD4, which binds MHC class II molecules. A remarkable feature of the CD4-MHC class ...

People with HIV who have moderate immune suppression appear to be at greater risk of severe COVID-19 'breakthrough' infection after vaccination, according to a new study. People with HIV who have ...

Researchers at Winship Cancer Institute of Emory University have identified a novel type of immune cell, called the stem-like CD4 T cell, that plays a pivotal role in anti-tumor immunity. The ...