The tendency of actin to polymerize initially thwarted crystal production. Holmes and colleagues overcame this by complexing rabbit skeletal actin with DNase I, thereby preventing polymerization and ...

This is a preview. Log in through your library . Abstract The organization of actin in mouse neuroblastoma and chicken dorsal root ganglion (DRG) nerve cells was investigated by means of a variety of ...

The actin and myosin complex (actomyosin) generates contraction force of a muscle utilizing the adenosine triphosphate (ATP) hydrolysis reaction. Many attempts have thus been made to explain the ...

During each heartbeat, cardiac contractility results from calcium-activated sliding of actin thin filaments toward the centers of myosin thick filaments to shorten cellular length. Cardiac ...

Skeletal and heart muscles contract and relax upon sliding of parallel filaments of the proteins myosin and actin. Nebulin, another long slender protein, which is present only in skeletal muscle, ...

Myosin in muscles behaves in a unique way, which might explain why muscles have such strong contractile power. A cartoon showing the asymmetry in the weak binding between myosin and actin that biases ...

Scientists at the Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association say they have developed a mouse model that enables them to look inside a working muscle and identify the ...