As a class, sodium–glucose transporter 2 inhibitors are novel drugs initially developed for glycemic control in patients with type 2 diabetes. [Cowie MR, et al. Nat Rev Cardiol. 2020;1a] Their primary ...

Proteins spanning the membranes of cells of the intestine and kidney use sodium-ion gradients to take up glucose, enabling water absorption, too. The structures of these transporter proteins have now ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. “Sodium-glucose transport protein 2 (SGLT2) inhibitor ...

In a recent rat study, scientists found that blocking both SGLT1 and SGLT2 worked better than blocking SGLT2 alone for treating high blood pressure caused by too much salt and for preventing kidney ...

Sodium-glucose cotransporter-2 inhibitors (SGLT2i), or gliflozins, are medications used in the treatment of type 2 diabetes mellitus (T2DM). They are designed to lower high blood glucose levels ...

Although clinical trials have linked diabetes medications called sodium glucose transport-2 inhibitors to higher bone fracture risks, a large study found no additional risks when the medications were ...

High blood sugar levels can cause blood sodium levels to appear low. However, this is usually due to a dilutional effect. Doctors can use a sodium glucose correction formula to calculate accurate ...

One of the hallmarks of cancer cell development is its dependence on sugar, especially glucose, to grow and divide. Scientists have long been studying how to restrict or block this process that ...