Anyone who has used a standard fluorescence microscope has faced a familiar problem: when an object goes out of focus, its image becomes blurred but does not disappear. This simple problem presents a ...

In recent advancements in life sciences, optical microscopy has played a crucial role in acquiring high-quality three-dimensional structural and functional information. However, the quality of 3D ...

Peking University, May 23, 2025: A collaboration between team led by Xi Peng, researcher from PKU College of Future Technology, and Qu Junle from Shenzhen University developed an innovative approach ...

Ultramicrotomy is a specialized technique used for preparing extremely thin sections of materials for microscopic analysis, particularly in the fields of nanotechnology, biology, and materials science ...

Researchers have obtained the first high-resolution, three-dimensional images of a cell with a nucleus undergoing cell division. The observations, made using a powerful imaging technique in ...

The use of serial sectioning followed by tridimensional reconstruction is a convenient way to study the spatial morphology of any structure (cell or organelle). This method was applied to the study of ...