Titrated low-dose amitriptyline significantly improved irritable bowel syndrome (IBS) symptoms when used as a second-line treatment in the primary care setting, the randomized ATLANTIS trial showed.

Irritable bowel syndrome (IBS) is a chronic disorder that causes abdominal pain and is often associated with psychological distress. A recent systematic review of 32 randomized trials analyzed the ...

LAS VEGAS, Nevada — Low-dose tricyclic antidepressant therapy is effective in treating moderately severe functional symptoms in patients with inflammatory bowel disease (IBD) who are not experiencing ...

An inexpensive medication long used for depression and migraines now has a clinical trial to back up its off-label use for another condition that lowers quality of life: irritable bowel syndrome (IBS) ...

Selective serotonin reuptake inhibitors (SSRIs) are among the most widely prescribed medications in the United States, primarily for managing depression. While SSRIs emerged as antidepressants during ...

Irritable bowel syndrome (IBS) is one of the most common gastrointestinal conditions you can get. It’s defined as abdominal pain or discomfort with, ahem, “altered” bowel habits over a period of time.

Obstetricians and psychiatrists are concerned about a recent FDA panel spreading misinformation about the potential harms of using SSRIs during pregnancy and postpartum. Should pregnant women and new ...