But the biggest knock on the beloved ingredient is that some people just can’t tolerate it, and for many others, there is an adjustment period during which your skin becomes dry and irritated. If you ...

Retinaldehyde, an intermediate metabolite between vitamin A and retinoic acid, is present at biologically active concentrations in fat tissue, where it antagonizes PPAR-γ activity, inhibiting ...

AKR1B10 is a human aldo-keto reductase (AKR) found to be elevated in several cancer types and in precancerous lesions. In vitro, AKR1B10 exhibits a much higher retinaldehyde reductase activity than ...

The temporal progression of retinal degeneration and early-stage idebenone treatment in the Pde6b rd1/rd1 mouse model of retinal dystrophy Figure 1: Rald and Rald-metabolizing enzymes in rodent fat.

The skincare benefits of retinol are numerous and well-known. From smoothing out fine lines to treating acne, it's a powerhouse ingredient for your skin. But with every benefit comes a downside, and ...

If you’re looking to add a powerful retinoid to your skincare routine without the usual redness or flaking, Medik8’s Crystal Retinal might just be your skincare routines new MVP. Often described by ...

Metro journalists select and curate the products that feature on our site. If you make a purchase via links on this page we will earn commission – learn more After a skincare product that’ll target ...