Schematic depiction of the principal components of epitranscriptomic mechanisms and their involvement in malignant hematopoiesis. Writers and erasers of main reversible methylations are represented in ...

University of Chicago researchers have developed a liquid biopsy test based on modification patterns in microbiome-derived cell-free RNA that predicts colorectal cancer (CRC) with greater accuracy ...

A new tool called SigRM helps researchers study RNA modifications in individual cells, improving our understanding of how genes are regulated. Researchers have developed a new tool that will help ...

New research published in Nature has uncovered powerful evidence that may explain why a new chemical modification of RNA is made in cells. The findings, by Ryan Flynn, MD, Ph.D., in collaboration with ...

The human body has to protect itself from pathogens and infectious agents, and there are a variety of ways for the immune system to sense foreign invaders, and react to the threats they may pose. But ...

To understand more fully the role of RNA and its modifications in living systems, researchers will need robust, reproducible, and accessible tools and techniques capable of identifying all RNA ...

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells ...

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications. A ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message, or mRNA, which is then converted into protein. Although DNA remains the same ...

Suggested Citation: "2 Importance and Impacts of RNA Modifications in Biology, Disease, Medicine, and Society." National Academies of Sciences, Engineering, and Medicine. 2024. Charting a Future for ...