Life events and stress also play a big role. Losing a loved one, going through a divorce, facing financial trouble, or ...

Patients with type 2 diabetes often have comorbid major depressive disorder, but the underlying neurobiological substrates are still poorly understood. The goal of this study was, therefore, to ...

As common as depression is—about one person in 10 experiences depression in any given year—it still eludes complete understanding. The trigger for depression can be almost any negative experience or ...

What are the differences between depression and "the blues"? DR. RICHARD FRIEDMAN: A typical patient with depression who's functioning in the world, who's working, but feeling miserable, has no ...

Since the 1960s, researchers have postulated that major depression stems from disruptions in the serotonin neurotransmitter system, but the evidence for that idea, though plentiful, was indirect. In ...

Depression, a pervasive and complex mental health condition, affects millions of lives worldwide. Yet, the roots of this condition are often elusive, leaving both sufferers and their loved ones ...

Anxiety and depression are two of the most frequently occurring mental disorders worldwide. Light-activated nerve cells may indicate how they are formed. By coupling nerve cell receptors to ...

Depression is characterized by a persistent low mood that can affect quality of life. If symptoms usually only occur in the winter months, it may be seasonal affective disorder (SAD), or major ...

Bill Valvo could sense that something was going very wrong with his health. He had worked for a software-development company in Fairfax, Va., for 10 years following a 22-year hitch with the Air Force, ...

Why is the age of onset (the first depressive episode) dropping? DR. CHARLES NEMEROFF: So whether or not the rate of depression is increasing might be a matter of debate. What isn't a debate is the ...

Depression is a state of unhappiness and hopelessness - a psychiatric disorder manifested by persistent feelings of dejection, lack of energy, poor concentration and sometimes suicidal thoughts. There ...