Mononuclear phagocytes can both promote and inhibit inflammation. A team has now shown that individual phagocytes in the central nervous system can play both roles, sequentially adopting different ...

A phase I study of lapatinib (LPT) and cetuximab (CTX) in patients with CTX-sensitive solid tumors. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I. This abstract does not include ...

Parts of this program prevent the immune system from destroying healthy organs or tissues, but might also leave a blind spot for detecting and fighting cancer." The authors studied immune mononuclear ...

BioIVT provides isolated peripheral blood mononuclear cells (PBMCs) from normal donors, which can be delivered fresh within 24 hours to specific locations or cryopreserved with demographic information ...

The effect of pH on phagocytosis of a mycobacterium and of yeast cells by rabbit monocytes was evaluated with direct counting techniques. A broad range for optimal phagocytosis was found which exceeds ...

Mechanisms of macrophage regulation mediated by iron-based mag netic nanomaterials. SOD, superoxide dismutase; POD, peroxidase; CAT, cata lase; NF-κB, nuclear factor-kappa B; MAPK, mitogen-activated ...

"Young" immune cells created by Cedars-Sinai investigators reversed signs of aging and Alzheimer's disease in the brains of laboratory mice, according to a study published in the journal Advanced ...

Population pharmacokinetics and pharmacogenomics of erlotinib: Effect of drug exposure on treatment outcomes in Japanese patients with non-small cell lung cancer. This is an ASCO Meeting Abstract from ...