The influence of dietary compounds on aging is a rapidly growing field of research. Amino acids, the building blocks of ...

Genetically predicted filtered coffee consumption is causally associated with lower HbA1c levels, while other coffee ...

A meta-analysis of 80,737 cases identifies five new variants and 22 risk genes, highlighting three potential drug targets for ...

Researchers have found in a new study that genetically predicted obstructive sleep apnea (OSA) is linked to a higher risk of diabetic nephropathy. The study indicates that BMI and high ...

Mendelian randomization is a study design that uses genetic variants as instrumental variables to test the causal effect of a (non-genetic) risk factor on a disease or health-related outcome. Since ...

Mendelian randomization is not affected by the confounding inherent in observational studies but it does rely on several assumptions, which can be hard to test Mendelian randomization can provide a ...

New evidence highlights prolonged sedentary behavior, particularly in desk-based jobs, as a significant and independent risk ...