Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. A team led by ...

Ether lipids (EL) are glycerophospholipids with a different structure and functional characteristics than fatty acids, thus requiring a specialized biosynthesis pathway. Peroxisomal fatty acyl-CoA ...

Interest in lipid nanoparticles (LNPs) as delivery vehicles for precision therapies in genetic diseases and cancers remains at an all-time high. Now, scientists from the University of Pennsylvania, ...

Scientists have discovered that the internal shape of tiny drug-delivery particles—called lipid nanoparticles—has a big impact on how well our cells absorb them, paving the way to more efficient ...

Chemerin is a key adipokine—a signaling protein released by adipose tissue—that regulates lipid metabolism and insulin sensitivity and thus is involved in many metabolic diseases such as obesity and ...

In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.