How an RNA-binding protein detects and responds to non-optimal codon usage in human cells

Human genes are written in long strings of three-letter units composed of four different nucleotides. These units—or ...

How do GLP-1 agonists affect gene expression?

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve ...

AI model predicts chemical effects on gene expression, speeding drug discovery

Inside a diseased cell, the genes are in chaos. Some are receiving signals to overproduce a protein. Others are reducing ...
Baylor College of Medicine

Study uncovers source of genetic variation influencing childhood brain tumors

Researchers still do not have a comprehensive picture of the factors that influence gene expression in human cancers. Understanding gene expression in cancer is important because it can reveal how the ...

Gene expression program linked to neurotransmission in the living human brain identified

Researchers have identified a distinct and reproducible gene expression program associated with neurotransmission in the ...
EurekAlert!

How do GLP-1 agonists affect gene expression?

Small (left) and large (right) condensates of the Mediator complex inside nuclei of a pancreatic beta cell-derived cell line. Salk researchers discovered that GLP-1s interact with the multi-protein ...