Glut1 protein may be a potential therapeutic target for kidney disease

Targeting and disabling a certain protein essential to transporting glucose properly through cells (Glucose Transporter 1, or ...
Nature

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

The glucose transporter GLUT1 at the blood-brain barrier (BBB) mediates glucose transport into the brain. Alzheimer's disease is characterized by early reductions in glucose transport associated with ...
Milwaukee Journal Sentinel

In the grip of a rare disease, 14-year-old 'has every right to be mad at the world and she's not'

Only 500 cases of GLUT1 deficiency have been described in medical literature, though some research suggests that it may occur more often and go undiagnosed. Even in the very small universe of GLUT1 ...
Science Daily

Low sugar uptake in brain appears to exacerbate Alzheimer's disease

A deficiency in the protein responsible for moving glucose across the brain's protective blood-brain barrier appears to intensify the neurodegenerative effects of Alzheimer's disease, according to a ...
Science Daily

Medicinal oil reduces debilitating epileptic seizures associated with Glut1 deficiency, trial shows

A rare metabolic disease that caused hundreds of seizures daily for a 6-year-old is now significantly under control as part of a clinical trial that uses a medicinal oil for treatment. Within hours, ...