ass spectrometry (MS) has evolved into one of the most sensitive analytical methods for the structural characterization of molecules. 1,2 Ionization is critical for volatilizing sample analytes into a ...

EI was first developed by Dempster in 1918 2 and can be considered a fairly harsh method of molecule fragmentation and ionization. In EI, the molecules of the analyte must be in the vapor phase to ...

Mass spectrometry (MS) is already perhaps the most popular analytical chemistry tool in drug discovery and development. Its use is ubiquitous in bioanalytical laboratories for drug and metabolite ...

To achieve the best results, using the right ionization method is essential. There are three main atmospheric pressure ionization (API) techniques that differ in their application concerning compound ...