Basic glucocorticoids (humans as cortisol, rodents as corticosterone) are crucial to controlling fetal bone histomorphology and functional maturity. 10 Nevertheless, maternal long-term use of ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, No. 49 (Dec. 7, 2004), pp. 17300-17305 (6 pages) Guanylyl cyclase B is the receptor for a small peptide ...

Retinoic acid receptors inhibit chondrogenesis, but their ability to block the cartilaginous scaffold of heterotopic endochondral ossification has not been explored. A study in mice shows that ...

Fluorescein-labeled antibodies to protein-polysaccharides from rat and calf cartilage were used for the histochemical localization of protein-polysaccharide in epiphyseal cartilage. There was less ...

In a new study published on 21 July 2023 by the journal Bone Research, a team of researchers from Johns Hopkins University, using a combination of lineage tracing and single-cell RNA sequencing (scRNA ...

"Historically viewed as mainly a “wear and tear” condition, new insights suggest that OA may be part of an evolutionary, age-related biological process rather than mainly driven by mechanical damage." ...

image: Tppp3+ tendon sheath progenitors expand at the heterotopic ossification (HO) induction site after Achilles tendon injury. a Schematic representation of HO induction, including complete Achilles ...

The skeleton is among the most commonly injured body tissues. Every year more than 16 million fractures of long bones occur in the United States. Fortunately, bone has excellent regenerative potential ...