Cytoplasmic dynein is a vital microtubule-based motor protein that drives retrograde intracellular transport, supporting essential cellular functions ranging from organelle positioning to cell ...

Movement signals life, and nowhere is this truer than inside a living cell. The millions of proteins and molecules within each of our cells bend, travel and conform in a complex but orchestrated ...

Diverse cellular processes require many tiny force-generating motor proteins to work in a team. Paradoxically, nature often chooses the weak and inefficient dynein motor to generate large persistent ...

A team led by scientists at The Scripps Research Institute (TSRI), La Jolla, Calif, has determined the basic structural organization of a molecular motor that hauls cargoes and performs other critical ...

image: This artist's conception -- which will be the cover art for the April 16 issue of the journal Cell-- shows three molecular motors that help move cells and things inside them. The details of how ...

(Nanowerk News) An international team of scientists led by the University of Leeds has shed new light on the little-understood motor protein called dynein, thought to be involved in progressive ...

These proteins are vital to complex life, forming the transport infrastructure that allows different parts of cells to specialise in particular functions. Until now, the way they move has never been ...

This is a preview. Log in through your library . Abstract Degenerative disorders of motor neurons include a range of progressive fatal diseases such as amyotrophic lateral sclerosis (ALS), ...

New research has uncovered how a "wimpy" protein motor works with two other proteins to gain the strength necessary to move nerve cells and components inside them. The findings shed light on brain ...

During mitosis in budding yeast, dynein moves the mitotic spindle into the mother-bud neck. We have proposed an offloading model to explain how dynein works. Dynein is targeted to the dynamic plus end ...

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