Albina Orlova, Alexander Shvetsov, Vitold E. Galkin, Dmitry S. Kudryashov, Peter A. Rubenstein, Edward H. Egelman, Emil Reisler, David J. DeRosier Proceedings of the ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 24 (June 11, 2019), pp. 12084-12093 (10 pages) Srv2p/CAP1 is an essential regulator of actin turnover, ...

Supercomputer simulations allocated by XSEDE on TACC's Stampede2 have helped solve the mystery of how actin filaments polymerize. Researchers employed all-atom molecular dynamics to show structural ...

Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing ...

Right: Cells whose actin filaments were disrupted. Time zero indicates the beginning cell plate formation. The phragmoplast microtubules are yellow, and the cell plate is magenta. Using microscopic ...

An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles. Actin filaments -- protein structures critical to living movement ...

The dynamic processes that occur during the growth of actin, via polymerization, and the breakdown of actin both play significant roles in cellular mechanisms like migration and adhesion. Due to the ...

Actin cytoskeleton is essential for eukaryotic cells. To exert its countless cellular functions, actin undergoes dynamic remodeling orchestrated by the large number of actin-interacting factors.

Some cells, such as immune cells, are highly mobile—they constantly remodel their shape, migrate toward a wound that needs to be closed or chase down bacteria in the bloodstream. This mobility is ...