Results highlight potential diabetes drug target and role for ceramides in sensing nutrition. A small chemical change — shifting the position of two hydrogen atoms — makes the difference between mice ...

Serious damage to short-term kidney function—known as acute kidney injury, or AKI—can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ...

Dr. Scott Summers, the lead researcher, said they were amazed by the results. By turning off ceramides, they completely stopped the damage from AKI. The kidneys kept working normally, and the ...