Researchers have visualized at the molecular level how formins bind to the ends of actin filaments. This allowed them to uncover how formins mediate the addition of new actin molecules to a growing ...
An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles. Actin filaments -- protein structures critical to living movement ...
Right: Cells whose actin filaments were disrupted. Time zero indicates the beginning cell plate formation. The phragmoplast microtubules are yellow, and the cell plate is magenta. Using microscopic ...
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Dancing proteins keep cells moving: Redefining the function and role of key factors in actin filament disassembly
Some cells, such as immune cells, are highly mobile—they constantly remodel their shape, migrate toward a wound that needs to be closed or chase down bacteria in the bloodstream. This mobility is ...
The discovery opens the door to healthier aging in humans. The cytoskeleton provides most cells with their shape, structure, and internal organization. In turn, the cytoskeleton relies on a type of ...
Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing ...
Research has demonstrated that actin waves propagate via actin polymerization on the substrate-attached cell membrane at the wave’s front and disassembly at the back of the wave. 4 Proteins named Arp2 ...
This is a preview. Log in through your library . Abstract Phototropins (phot1 and phot2 in Arabidopsis thaliana) relay blue light intensity information to the chloroplasts, which move toward weak ...
When a nerve fiber in the spinal cord is severed, its repair may require that something else be severed: actin. In mature neurons of the central nervous system, actin is stable; that is, actin ...
Formins are made of two identical parts (red, orange) that encircle the actin (grey) filament in a ring-like conformation. “Our discovery allows us to interpret decades of biochemical studies on ...
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