Albina Orlova, Alexander Shvetsov, Vitold E. Galkin, Dmitry S. Kudryashov, Peter A. Rubenstein, Edward H. Egelman, Emil Reisler, David J. DeRosier Proceedings of the ...

This is a preview. Log in through your library . Abstract Small heat shock protein HSPB7 is highly expressed in the heart. Several mutations within HSPB7 are associated with dilated cardiomyopathy and ...

Supercomputer simulations allocated by XSEDE on TACC's Stampede2 have helped solve the mystery of how actin filaments polymerize. Researchers employed all-atom molecular dynamics to show structural ...

The dynamic processes that occur during the growth of actin, via polymerization, and the breakdown of actin both play significant roles in cellular mechanisms like migration and adhesion. Due to the ...

Researchers have discovered that terahertz (THz) wave irradiation activates the filamentation of actin protein. The discovery offers a new possibility for the manipulation of cellular functions. A ...

Actin filaments — protein structures critical to living movement from single cells to animals — have long been known to have polarity associated with their physical characteristics, with growing ...

How can a nanometer-scale protein generate and transmit forces to control cell shape changes across micrometer-scale distances? A crawling cell pushes its plasma membrane forward. The protein is actin ...

Brown scientists have described a previously unknown but critical blood-clotting role for Arp2/3, a complex of seven proteins found in animal and plant cells. Reporting in the June 15 issue of Blood, ...

Metastases occur when cancer cells leave a primary tumor and spread throughout the body. For this, they have to break connections with neighboring cells and migrate to other tissues. Both processes ...