Objectives The TREAT EARLIER trial showed in clinically suspect arthralgia (CSA) that methotrexate induced reductions in ...

COPENHAGEN -- Methotrexate helped high-risk individuals with aching and inflamed joints, but who didn't yet have overt rheumatoid arthritis (RA), avoid that diagnosis for close to 2 years in a ...

NEW YORK CITY -- Postoperative intravitreal methotrexate for retinal detachment led to a significant reduction in reoperation and improved visual acuity, a retrospective chart review showed. The ...

If you’re looking at treatment options for psoriasis, arthritis, or certain kinds of cancer, you may want to learn more about methotrexate. For more details on methotrexate’s uses and more, see this ...

Patients who take methotrexate for a variety of immune-mediated inflammatory diseases and pause taking the drug following receipt of a COVID-19 vaccine dose did not have a higher risk of disease flare ...

Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects. Now new research published at the ATS 2025 International ...

Patients with Wegener's granulomatosis often undergo treatment with cyclophosphamide in order to induce disease remission. Methotrexate and leflunomide have been proposed for maintaining remission ...

Adalimumab monotherapy and combination with methotrexate showed similar drug survival and PASI75 response rates in plaque psoriasis patients. Methotrexate reduced antidrug antibody levels but did not ...

For decades, methotrexate has formed the foundation of therapy in RA, either alone or in combination with other drugs; however, its mechanisms of action remain poorly understood, and many patients ...

SaveHealth reports on common rheumatoid arthritis medications, highlighting their effectiveness, side effects, and cost ...

Subcutaneous tocilizumab, either as monotherapy or in combination with methotrexate, demonstrated greater efficacy than methotrexate alone and was well tolerated in patients with active rheumatoid ...

New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that tuberculosis (TB) screening and ongoing clinical care is needed for people on methotrexate ...