T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...
A research team has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This discovery deepens the understanding of a new type of ...
Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or ...
In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug ...
A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...
Northwestern Medicine scientists have discovered how calcium signaling channels in microglia—the primary immune cells of the brain—regulate neuroinflammation and promote the development of behaviors ...
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