Introduction Lower extremity Ilizarov surgery, a common procedure for correcting bone deformities, is often associated with reduced physical activity (PA) and functional decline. The home-based PA ...

Background Alcohol use disorder and treatment-resistant depression (TRD) often co-occur, presenting a major clinical challenge with limited effective treatments. However, ketamine produces rapid ...

A protocol deviation or violation is any departure from the study procedures or treatment plans as specified in the IRB-approved protocol. Protocol deviations occur when an investigator does not ...

List of acronyms and abbreviations commonly used in clinical trials research. Clinical Trials Glossary List of terms commonly used in clinical trials research. Glossary of Medical Terms in Lay ...

Researchers develop a modified high-resolution magnetic resonance imaging technique for determining the location of ...

A single IRB (sIRB) of record will be used in the ethical review of non-exempt human subjects research protocols funded by federal agencies that are carried out at more than one site in the United ...

The U.S. Food and Drug Administration (FDA) published the draft guidance “Protocol Deviations for Clinical Investigations of Drugs, Biological Products, and Devices,” which provides advice for ...

Follow the step-by-step instructions below to successfully maintain and close a protocol with the IRB. Instructions below include information about continuing reviews, amendments, event reporting (new ...