Scientists have identified a protein that may be key to proper sperm formation. Without it, male mice produced no viable sperm, they found. A team at the RIKEN Center for Biosystems Dynamics Research ...

Researchers have identified a novel Heat Shock Factor (HSF), designated as HSF5, which plays a crucial role in the completion of meiosis and the activation of genes essential for sperm formation. This ...

For decades, sperm were thought to become fully active the moment they entered the female reproductive tract. New research suggests otherwise. A temperature-sensitive switch inside sperm cells may ...

A study finds that brief immune stress in male mice can leave lasting metabolic and behavioral effects in offspring through ...

The human body is full of checks and balances that ensure correct growth, development, and function of all our different systems. Now, researchers from Japan have reported a newly discovered protein ...

Electron microscope image of mouse sperm head. The mouse sperm head is characterized by a crescent shape, whereas in TEX38-deficient sperm the head is bent backward 180 degrees. Osaka, Japan – The ...

Male infertility remains a significant clinical and social challenge, with genetic factors playing a crucial role in the aetiology of the condition. The genetic landscape is remarkably complex, ...

Deletion of hsf5 in mice results in the impaired development of testis (left), and the absence of spermatids and spermatozoa (right), which leads to the failure of sperm formation. Kumamoto University ...