Spatial proteomics enables scientists to investigate protein organization at the subcellular, cellular, and tissue levels, including in pathological contexts. Using technologies that help researchers ...

To study biological processes, scientists often take snapshots of the molecules in cells, such as proteins and nucleotides, at specific points in time. In spatial biology, they can leverage molecular ...

In a recent study published in Nature, researchers investigate the spatial organization of cancer cells and the tumor microenvironment by analyzing over one hundred tumor sections across six types of ...

Left: Imaging of lamin A/C structures in a physically expanded nucleus from an individual with progeria. Right: Same, but with 3D genomic reads overlaid in their original spatial locations, colored by ...

Like workers at a factory or office, proteins in a cell must be in the right department to do their jobs. But scientists have yet to fully map the cell’s organization, much less determine how these ...

Tsukuba, Japan—Cells contain various organelles, including the nucleus, which stores genetic information, and mitochondria, which generate the energy essential for biological processes. While these ...

An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...