Official advice on the NHS website adds: "Amitriptyline is from a group of medicines called tricyclic antidepressants.

The prescription medication is commonly used to help manage nerve pain, depression and migraines ...

Preventive antimigraine therapy (PAM) should probably not be considered until the headache frequency exceeds 1 per week. PAM is associated with significant side effects and often with tachyphylaxis ...

Despite amitriptyline missing the primary endpoint of significantly improving pain relief, disability, and work-related outcomes at 6 months for people with chronic low back pain, shorter term ...