Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...
In the field of neuro-oncology, the dual topics of cellular metabolism and the tumor microenvironment (TME) have gained ...
The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling ...
A mechanism underlying neutrophil reprogramming in brain cancers has been uncovered, illuminating potential therapeutic targets to stop their pro-cancer effect. Tumor-infiltrating neutrophils are ...
Researchers have defined a new genetic disease caused by a mutation in the IVNS1ABP gene. The condition marks a rare ...
Brain fog can be scary. It might appear innocently, like losing your car keys or forgetting what date you scheduled that appointment on. Some of this memory loss is normal—it’s just a natural side ...
When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is also altered. This process of neuronal ageing — inevitable with ...
Researchers have engineered a dual-targeting nanocarrier that safely sneaks potent chemotherapy past the blood-brain barrier.
A team from the Spanish National Cancer Research Centre (CNIO) has discovered a novel way in which tumor cells alter the ...
As cell therapy advances toward clinical reality, iPSC-derived cellular products, in vivo reprogramming strategies, and ...
AI identifies a brain rewiring mechanism where the healthy side stays younger to compensate for stroke damage, offering new ...
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