DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break involves the severing of both strands of the DNA double ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

Researchers show that loss of the SPRTN enzyme lets DNA–protein crosslinks accumulate, leak DNA into the cytoplasm, activate ...

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...

Particle therapy, including proton and carbon ion radiotherapy, represents a major advancement in cancer treatment due to its ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Francesca Storici, Georgia Institute of Technology (THE CONVERSATION) Your DNA is ...