Preferential MOP agonists such as oxycodone are often required for effective management of moderate to severe pain but come with significant risks of addiction and overdose – – With Dual NMR agonists, ...

The nonapeptide Oxytocin is a cyclic nine-amino‐acid peptide that has long been studied for its possible roles in ...

Peptides have emerged as critical tools in the investigation of physiological homeostasis, specifically in how biological systems manage energy substrates and recover from physical trauma. By ...

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

Partial opioid agonists have mixed or limited action when they bind to your opioid receptors. So, doctors often use them to treat opioid use disorder. Protein receptor sites are like keyholes on the ...

Patients with hereditary angioedema using deucrictibant as an on-demand treatment for attacks achieved onset of symptom ...

However, the measurement of sIL-2R is simple compared to the complex story behind this biomarker that has become so central to the study of immune-mediated disease. Why measure soluble interleukin-2 ...

The most important class of drug discovery targets today is undoubtedly the class of G-protein coupled receptors (GPCRs). These receptors account for more than 30% of all targets currently under ...