Researchers present BioEmu – a new AI model that rapidly and accurately predicts the full range of shapes a protein can adopt, offering a faster, cheaper alternative to traditional molecular ...
Using a tool to solve a protein's structure, for most researchers in the world of structural biology and computational chemistry, is not unlike using the Rosetta Stone to unlock the secrets of ancient ...
Over the past decade, however, a wave of technological advances has begun to expand the druggable proteome. These include covalent inhibitors (such as sotorasib), chemical proteomics, and AI-enabled ...
In a new study published in GEN’s sister peer-review journal, GEN Biotechnology, titled, “Exploring Structure-Function Relationships in Engineered Receptor Performance Using Computational Structure ...
The GPCRact AI model goes beyond AlphaFold3 by predicting whether drugs functionally activate G-protein-coupled receptors through allosteric signaling.
BUFFALO, N.Y. – University at Buffalo researcher Thomas Grant has been awarded a $2.18 million federal grant to create a new artificial intelligence-powered tool that improves scientists’ ...
The new AI-powered workflow helps scientists identify which plant genes control the best microbial partnerships. This accelerates the engineering of microbiomes that help plants grow faster, require ...
Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and ...
Researchers have developed a diagnostic panel that identifies cognitive decline by analyzing how blood proteins fold. This ...
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