Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 32 (August 10, 2021), pp. 1-11 (11 pages) Family with sequence similarity 20C (Fam20C), the major protein ...
(MEMPHIS, Tenn. – December 18, 2025) Scientists at St. Jude Children’s Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows ...
As society ages, the number of patients with heart failure is rapidly increasing. The progression of the disease is caused by excessive growth of fibrotic tissue in the heart, known as fibrosis. A ...
In a recent study published in the journal Nature Machine Intelligence, researchers developed "DeepGO-SE," a method to predict gene ontology (GO) functions from protein sequences using a large, ...
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Two isoforms of a cellular energy sensor play distinct, opposing roles in Alzheimer's disease
A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest University School of Medicine synthesizes emerging evidence that two ...
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