WT1 to enhance proliferation and to impede apoptosis in KRAS-mutant NSCLC via targeting cMyc. This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting I. This abstract does not include a ...

Single-cell RNA sequencing data are useful for studying cell phenotypes and function. However, deciphering the clonal relationships of cells is critical to understanding the patterns of cell migration ...

Liquid biopsy is increasingly recognized as a promising tool for cancer detection and treatment monitoring, yet its effectiveness is often limited by the extremely low levels of tumor-derived DNA ...

Genetic mutations cause hundreds of unsolved and untreatable disorders. Among them, DNA mutations in a small percentage of cells, called mosaic mutations, are extremely difficult to detect because ...

Breast cancer remains a significant health concern worldwide, with diverse molecular subtypes that necessitate personalized therapeutic approaches. Recent advances have highlighted the importance of ...

As new variants of the SARS-CoV-2 virus continue to emerge, concerns have been raised about the performance of rapid antigen tests. The team, which was funded by NIH's Rapid Acceleration of ...

Using the LightCycler 480 System for Discovery and Analysis of Genetic Variation LightCycler® Real-time PCR Systems from Roche (www.roche.com) are efficient platforms for genetic variation research.

Bryan Tieman is a Principal Scientist in the Diagnostics Division of Abbott Laboratories (IL, USA) and is a member of the Biologics Discovery Group where he creates binding agents and targets for the ...