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Multiplex Ligation-dependent Probe Amplification (MLPA)

Multiplex ligation-dependent probe amplification (MLPA) is a technique to detect copy number changes using polymerase chain reaction . This requires only 20 ng of sample DNA and can distinguish ...
ascopubs.org

Screening for genomic rearrangements in BRCA1 and BRCA2 genes in 16 Peruvian breast cancer families by Multiplex Ligation-dependent Probe Amplification (MLPA).

Potential germline relevance of tumor testing and the need for genetic referral. This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting I. This abstract does not include a full text ...
ascopubs.org

Quantitative copy number analysis by multiplex ligation-dependent probe amplification (MLPA) of BRCA1-associated breast cancer regions identifies BRCAness, and as such ...

Improving detection methods for PIK3CA mutations in breast cancer using peripheral blood from patients with metastastic breast cancer (MBC). This is an ASCO Meeting Abstract from the 2011 ASCO Annual ...
The American Journal of Managed Care

Novel Screening Method Shows Promise in Detecting SMA

Researchers have developed a new line method (NLM) that showcased benefits for genetic screening in spinal muscular atrophy (SMA). In the last decade, treatment options for spinal muscular atrophy ...