Earlier this week, a team of researchers announced that they’d made a discovery about how we inherit mitochondrial dna from ...
Doubly uniparental inheritance (DUI) of mitochondrial DNA (mtDNA) represents a rare and intriguing deviation from the standard model of strictly maternal inheritance. In bivalves, DUI manifests as the ...
The AHA recommended whole exome or whole genome sequencing as first-line diagnostic tools for mitochondrial diseases.
Geneticists looking inside the nuclear genome for mutations that contribute to disease have long relied on a principal known as constraint modeling, which allows researchers to assess the degree of ...
University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited. Dr. Anne Hahn and Associate Professor Steven Zuryn from UQ's ...
In most eukaryotes, the inheritance of mitochondrion and its DNA (mtDNA) is strictly maternal, despite the fact that a spermatozoon can inject up to 100 functional mitochondria into the oocyte during ...
Recombination occurs in human mitochondrial DNA, says a team from the Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, in a “proof of concept” paper in Science this week that ...
In September 6 Nature, Sofia Berlin and Hans Ellegren from Uppsala University, Sweden, examine the controversial clonal inheritance theory for vertebrate mitochondrial DNA (mtDNA) by following ...