A Dartmouth study published in Nature Communications reveals that immune cells in the brain use a surprising two-step process ...

While amyloid β plaques are hallmarks of Alzheimer’s disease (AD), recent research suggests that they aren’t the only players in the neurodegenerative disorder. Genome-wide association studies and RNA ...

A microglia replacement approach demonstrates that brain macrophages with patient mutations from Aicardi–Goutières syndrome, a genetic, brain predominant interferonopathy, are sufficient to drive ...

A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, inside the brain, another "crew" of responders is busy clearing debris and ...

“By the time we examine an autopsied brain-tissue sample, a pathologist will have rinsed it with alcohol, removing lipids,” said Tony Wyss-Coray, PhD, the D. H. Chen Professor II, a professor of ...

A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer's pathology in other ways. A rare but potent genetic ...

Add Yahoo as a preferred source to see more of our stories on Google. Microglial receptor ADGRG1 helps immune cells eat amyloid plaques and may offer new hope for Alzheimer's treatment. (CREDIT: ...

During development, there are known sex-related differences in how microglia function. But into adulthood, there was thought to be less variation in how they behave. Microglia maintain neuronal ...

A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, inside the brain, another “crew” of responders is busy clearing debris and ...

In the search for answers about Alzheimer’s disease, researchers are taking a close look at the immune system of the brain. A new study uncovers how a key immune cell, called a microglia, might be the ...