Major histocompatibility complex (MHC) polymorphism is thought to be driven by antagonistic coevolution between pathogens and hosts, mediated through either overdominance or frequency-dependent ...
Francois Guillemot, The Chicken Major Histocompatibility Complex (MHC): Evolutionary Conserved Class I and Class II Genes Are Closely Associated with Non-MHC Genes, American Zoologist, Vol. 31, No. 3 ...
The result is one molecule that can be both a checkpoint degrader and a cancer vaccine ( Nature 2026, DOI: 10.1038/s41586-025 ...
New light has been thrown on how humans choose their partners. Research has shown that people with diverse major histocompatibility complexes (MHCs) were more likely to choose each other as mates than ...
The anti-tumor immune response involves a series of complex steps mediated by various immune cells and signaling molecules.
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