When compared to tumors from European American men with mCRPC, African American men with mCRPC demonstrated a higher expression of MYC pathway genes and lower expression of IFN-γ, IL-6/JAK/STAT3 and ...
CARD14 directly binds and regulates MYC, a protein involved in controlling cell growth that can contribute to cancer when it malfunctions. A study published in Cell Reports shows that the proper ...
Beyond direct approaches, the review also emphasizes indirect targeting strategies, including inhibition of MYC transcription or translation, promotion of protein degradation, and synthetic ...
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