In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

A multinational research team led by researchers at Institute of Science Tokyo, RIKEN, and the University of Toronto has revealed how a tryptophan-rich allosteric communication network regulates ...

Targeted modulation of certain intracellular signaling proteins could represent an exciting new approach to drug development.

Researchers report a drug discovery strategy using tailor-made cyclic peptides to target β-arrestins, key regulators of ...

Dental pulp regeneration remains a major clinical challenge. Researchers have discovered that SMAD7 directly forms a ...

A synthetic tripeptide inspired by snake venom is opening new investigative routes into cellular signalling and structural ...

Dental pulp injury caused by trauma or deep caries often leads to inflammation, tissue necrosis, and eventual loss of tooth ...

Biopsies from people with persistent post-COVID-19 taste disturbance have revealed reduced expression of a key signalling ...