No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

Alopecia refers to hair loss and can affect the scalp, eyebrows, eyelashes, and other areas of the body. There are different types of alopecia including androgenetic alopecia, alopecia areata, anagen ...

The human genome contains about 23,000 genes, but only a fraction of those genes are turned on inside a cell at any given time. The complex network of regulatory elements that controls gene expression ...

Scientists at the Icahn School of Medicine at Mount Sinai and collaborators have identified novel genetic interactions that may contribute to congenital heart disease (CHD), a common birth defect.

Transcriptional regulation is a fundamental biological process where proteins interact with deoxyribonucleic acid (DNA) to ...

The Joint Open Genome and Omics Platform 1.0 (JoGo 1.0) catalogs 19,194 human genes with a novel naming system. Researchers expect the database to benefit medicine and genomics, and to provide a ...

Infants of mothers with diabetes have a three- to five-fold increased risk of congenital heart defects. Such developmental defects are likely caused by a combination of genetic and environmental ...

Genetic testing for chronic myeloid leukemia (CML) can tell doctors if someone has leukemia, what type they may have, and whether treatment is working. The tests look for atypical changes in certain ...