Sometimes, in genetics, two wrongs do make a right. A research team has recently shown that two harmful genetic variants, ...

No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

We know the genes, but not their functions—to resolve this long-standing bottleneck in microbial research, a joint research team has proposed a cutting-edge research strategy that leverages artificial ...

Explore RNA interference methods, comparing siRNA and shRNA for gene knockdown, their mechanisms, advantages, and ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

We know the genes, but not their functions.” To resolve this long-standing bottleneck in microbial research, a joint research ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Summary: Researchers have created a new experimental model that reveals how changing a key Alzheimer’s risk gene can shift the brain from vulnerability toward resilience. By switching a high-risk gene ...

Could a gene regulatory network in gut microbes have evolved its elaborate and tightly regulated molecular machinery only to pump out antibiotics indiscriminately? Researchers from the Institute of ...