Unprecedented views of the interior of cells and other nanoscale structures are now possible thanks to innovations in expansion microscopy. The advancements could help provide future insight into ...

Microscopy is an imaging technique that enables us to see a world that would otherwise be invisible to us. Once upon a time, visualizing cells, microbes and other entities not perceptible to the naked ...

Unlike other modes of microscopy that employ sophisticated optical equipment to acquire high-resolution images, expansion microscopy enlarges biological specimens physically enabling nanoscale image ...

A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before ...

A cell's identity is based on the genes it expresses, and scientists have been studying gene expression mechanisms for many years. But the process involves molecules that are too small to see, until ...

A pandemic-era breakthrough has allowed scientists to literally expand our view of plankton. By using ultrastructure expansion microscopy, researchers visualized the inner workings of hundreds of ...

A technique called expansion revealing microscopy separates molecules in cells before fluorescence labeling, uncovering unseen nanostructures for the first time. A research group at MIT (MA, USA) has ...

Expansion microscopy (ExM) is a route to bioimaging in which a crosslinked swellable hydrogel is used to physically expand fluorescently labelled tissues without disturbing the cellular structure.