A seminal paper by Miller and Brody [1] clearly laid the general framework on why we should abandon the term "clinical equipoise" in research. Their paper argued that the concept of equipoise (also ...

Clinical equipoise, or uncertainty about which treatment is best for a patient, is widely viewed as essential for an ethical RCT. The authors argue that clinical trials that violate equipoise are ...

Discordance in Human Epidermal Growth Factor Receptor 2 (HER2) Phenotype Between Primary Tumor and Circulating Tumor Cells in Women With HER2-Negative Metastatic Breast Cancer Central to the argument ...

NOTHING I have seen this racing year was quite so amazing as the victory of Equipoise in the Pimlico Futurity. It is not unusual for a horse to win after getting off to a poor start, but I don’t think ...

For more than a decade, the U.S. Preventive Services Task Force (USPSTF) [23] has published a ranking of clinical evidence. [24] The rankings, however, are based on what clinical investigators have ...